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Always consult a qualified medical provider before starting treatment to ensure suitability

In one meta-analysis of RCTs, metformin worked about three times as well when starting a new antipsychotic in first-episode psychosis (about a 13-pound difference from placebo) compared with its use after chronic antipsychotic treatment (about a 4-pound difference from placebo) (De Silva VA et al, BMC Psychiatry 2016;16(1):341)

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However, an excessive amount of ROS and RNS results in the oxidation of biological molecules such as lipids, proteins, and DNA